BPS Program Book 2014

2370-P os B oard #B62 CONTEXT-DEPENDENT FOLDING: SEQUENCE-ENCODED STRATEGIES FOR STABILIZING A PROTEIN SUBDOMAIN IN ISOLATION. Sabriya N. Rosemond , Kambiz H. Hamadani, Jamie H.D. Cate, Susan Marqusee 2371-P os B oard #B63 DENATURANT PROBES QUANTIFY THE PREFERENTIAL BURIAL OF AMIDE SURFACE IN FORMING THE KEY TRANSITION STATE AND EARLY INTERMEDIATES IN PROTEIN FOLDING. Rituparna Sengupta , Emily J. Guinn, Wayne S. Kontur, Oleg V. Tsodikov, Irina Shkel, M. Thomas Record Jr. 2372-P os B oard #B64 ALTERATION OF THE CYTOCHROME C FOLDING PATHWAY IN SOLUTION AND WITHIN SOL-GEL GLASSES BY ADDITION OF HOFMEISTER SALTS. Eric S. Peterson , Sean J. Steinke 2373-P os B oard #B65 PROTEIN-FOLDING STUDIES USING HYBRID TIRF SMFRET-MAGNETIC TWEEZERS. Samuel M. Leachman , Christian A. M. Wilson, Susan Marqusee, Carlos Bustamante 2374-P os B oard #B66 DETERMINING SOLUTE EFFECTS ON PROTEIN FOLDING USING SINGLE MOLECULE FORCE SPECTROSCOPY. Emily Guinn , Bharat Jagannathan, Susan Marqusee 2375-P os B oard #B67 EXPLORINGTHE COMPLEX ENERGY LANDSCAPE OF PROTEIN UNFOLDING UNDER FORCE. Bharat Jagannathan , Susan Marqusee 2376-P os B oard #B68 IS REFOLDING OF LYSOZYME TEMPLATE-DRIVEN. Sushanth Kumar , T.K.S Kumar 2377-P os B oard #B69 HIGH THROUGHPUT SCREENING OF FORMULATIONS TO OPTIMIZE THE THERMAL STABILITY OF THERAPEUTIC MONOCLONAL ANTIBODY. Elaine Kan , Anita Niedziela-Majka, Perry Weissburg, Scott Sellers, Roman Sakowicz 2378-P os B oard #B70 CONFORMATIONAL ANALYSIS OF ACTH/MELANOCORTIN PRECURSOR PROTEIN. Yuji Hidaka , Tadafumi Konogami, Shigeru Shimamoto 2379-P os B oard #B71 CONTRIBUTION OF METHIONINE OXIDATION TO AMYLOID FIBRIL FORMATION BY APOLIPOPROTEIN A-I. Gary Kwan Leung Chan, Andrzej Witkowski, Donald L. Gantz, Shobini Jayaraman, Giorgio Cavigiolio 2380-P os B oard #B72 international travel awardee USE OF FCS TO STUDY PROTEIN DENATURATION AND AGGREGATION. Moupriya Nag, Kallol Bera, Soumen Basak 2381-P os B oard #B73 education travel awardee AMYLOID-ß42 AGGREGATION ON CELLULAR MEMBRANES FACILITATES ITS CELLULAR UPTAKE. Sha Jin , Andreas Herrmann, Jan Bieschke 2382-P os B oard #B74 CLARIFYING THE INTERSECTION BETWEEN ALPHA- CRYSTALLIN B FUNCTION AND OLIGOMERIZATION BY ALTERING AGGREGATION CONDITIONS. Raysa Cabrejo, James Hebda, Patricia B. O’Hara

2358-P os B oard #B50 NATIVE ION MOBILITY-MASS SPECTROMETRY: FROM FLEXIBLE PROTEINS TO ION CHANNELS. Frank Sobott 2359-P os B oard #B51 HUMAN P52SHC CONFORMATIONAL BIAS AND LOCALIZATION IN C-SRC ACTIVATION. Yuko Tsutsui , Franklin A. Hays 2360-P os B oard #B52 NON-CANONICAL MODULAR DOMAIN INTERACTIONS DICTATE PKC α FUNCTION. Carter J. Swanson , Michael Ritt, William Wang, Michael Lang, John J. Tesmer, Margaret Westfall, Sivaraj Sivaramakrishnan 2361-P os B oard #B53 THE HISTIDINE BUTTON DICTATES THE CONFORMATION OF THE PH-SENSITIVE REGION OF TROPONIN I. Sandra E. Pineda-Sanabria , Ian M. Robertson, Peter C. Holmes, Brian D. Sykes 2362-P os B oard #B54 PURIFICATION AND STRUCTURAL ANALYSIS OF THE ANTI-VIRAL PROTEIN BST-2. Kelly E. Du Pont , Christopher E. Berndsen 2363-P os B oard #B55 PROBING G PROTEIN-COUPLED RECEPTOR DIMERISATION BY FRET AND DEER. Patricia M. Dijkman , Alan D. Goddard, Oliver K. Castell, Mark I. Wallace, Anthony Watts 2364-P os B oard #B56 TUG-OF-WAR BETWEEN THERMODYNAMIC STABILITY AND ACTIN-BINDING FUNCTION OF TANDEM CALPONIN- HOMOLOGY DOMAINS. Swati Bandi, Surinder Singh, Geoffrey Armstrong, Krishna Mallela 2365-P os B oard #B57 CHARACTERIZATION OF HUMAN, MOUSE, AND FROG RHODOPSIN MICRODOMAINS WITHIN NATIVE DISC MEMBRANES. Allison M. Whited-Holt , Paul S.-H. Park 2366-P os B oard #B58 RECONSTITUTION OF THE 26S PROTEASOME REVEALS FUNCTIONAL ASYMMETRIES IN ITS HETEROHEXAMERIC AAA+ UNFOLDASE. Robyn Beckwith , Evan Worden, Eric Estrin, Andreas Martin Protein Folding and Chaperones I (Boards #B59–#B85) 2367-P os B oard #B59 CROWD CONTROL: EFFECTS OF MACROMOLECULAR CROWDING ON EARLY EVENTS IN PROTEIN FOLDING. Eefei Chen , Vanessa Feng, Zachary Fong, Brian Rastian, Alex P. Rowe, Robert A. Goldbeck, David S. Kliger 2368-P os B oard #B60 VALIDATION OF THE CONSERVATION AND ROBUSTNESS OF FOLDING INITIATION SITES IN EVOLUTIONARILY RELATED PROTEINS. Masanari Matsuoka , Takeshi Kikuchi 2369-P os B oard #B61 STRUCTURAL AND FUNCTIONAL INTERACTIONS BETWEEN HSP90 AND THE CHOLERA TOXIN A1 SUBUNIT. Helen Burress , Michael Taylor, Tuhina Banerjee, Carly Bader, Suren A. Tatulian, Ken Teter

132

Biophysical Society 58 th Annual Meeting, San Francisco, California