BPS Program Book 2014

3638-P os B oard #B366 education travel awardee THE CELLULAR CONTENT OF NON-ERYTHROID SPECTRINS AND ANKYRINS IS MODULATED BY EXTERNAL FORCES. Eleni K. Degaga , Martin B. Forstner 3639-P os B oard #B367 SPATIO-TEMPORAL DYNAMICS OF SH2 DOMAIN RECRUITMENT DURING EPIDERMAL GROWTH FACTOR (EGF) RECEPTOR ACTIVATION. Dongmyung Oh , Mari Ogiue-Ikeda, Joshua A. Jadwin, Kazuya Machida, Bruce J. Mayer, Ji Yu 3640-P os B oard #B368 DOWNSTREAM TARGETS OF DOPAMINE RECEPTOR D3 ACTIVATION IN THE MOUSE PANCREATIC β -CELLS. Alessandro Ustione , David A. Jacobson, David W. Piston 3641-P os B oard #B369 FLUORESCENCE FLUCTUATION SPECTROSCOPY TO DETECT INTERACTIONS BETWEEN DOPAMINE RECEPTORS AND CALCIUM CHANNEL IN PANCREATIC Β -CELLS. Brittany Caldwell , Alessandro Ustione, David Piston 3642-P os B oard #B370 A LIVE CELL TIRF-MICROSCOPY BASED SCREENING ASSAY FOR FAST ANALYSIS OF RECEPTOR TYROSINE KINASE MODULATORS. Peter Lanzerstorfer , Shin-Ichiro Takahashi, Otmar Höglinger, Julian Weghuber 3643-P os B oard #B371 THE FRET SIGNATURES OF NON-INTERACTING PROTEINS IN CELLULAR MEMBRANES. Christopher R. King , Sarvenaz Sarabipour, Patrick Byrne, Daniel Leahy, Kalina Hristova 3644-P os B oard #B372 RESOLVINGTHE BRASSINOSTEROIDS SIGNAL TRANSDUCTION MECHANISMS BY SINGLE-MOLECULE ASSAYS. Song Song, Haijiao Wang, Xue-Lu Wang, Yan-Wen Tan 3645-P os B oard #B373 FAST AND LOCAL MECHANOTRANSDUCTION CONTROL VIA MAGNETIC NANOPARTICLES : MECHANICAL STIMULATION OF AUDITORY CELLS. Michael Lévy , Jae-Hyun Lee, Albert Kao, Ji-wook Kim, Seung-hyun Noh, Yung Ji Choi, Dolores Bozovic, Jinwoo Cheon 3646-P os B oard #B374 ROLE OF CALCIUM SIGNALING IN ENDOTHELIAL BARRIER FUNCTION. Judith A. Stolwijk , Christian W. Renken, Mohamed Trebak  Cardiac, Smooth, and Skeletal Muscle Electrophysiology II (Boards #B375–#B385) 3647-P os B oard #B375 OPTIMIZING RATE CORRECTION OF FIELD POTENTIAL DURATION, A BIOMARKER FOR QT RISK ASSESSMENT, IN HUMAN IPSC-CARDIOMYOCYTES. Greg Luerman , Carlos Obejero-Paz, Arthur M. Brown, Andrew Bruening-Wright 3648-P os B oard #B376 COMBINE USE OF INTRACELLULAR CALCIUM AND SARCOLEMMA VOLTAGE MEASUREMENTS TO DISTINGUISH MIXED CHANNEL EFFECTS INHUMAN INDUCED PLUTIPOTENT STEM CELLS DERIVED CARDIOMYOCYTES (HIPSC-CMS). Maria P. Hortigon-Vinagre , Emma L. Low, Iffath A. Ghouri, Robert Wallis, Francis L. Burton, Margaret A. Craig, Blake D. Anson, Godrey L. Smith

3649-P os B oard #B377 MULTIPARAMETRIC ONE-COLOR ASSAYS FOR FUNCTIONAL ASSESSMENTOF CARDIOMYOCYTES. Alex Savtchenko , Manuel Ruidiaz, EvanW. Miller, Wesley McKeithan, Susanne Heynen-Genel, Mark Mercola 3650-P os B oard #B378 A NOVEL APPROACH FOR EVALUATION OF DRUG-INDUCED QT PROLONGATION USING HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES. Min Li , Yasunari Kanda, Yuko Sekino, Tetsushi Furukawa, Junko Kurokawa 3651-P os B oard #B379 RANOLAZINE REDUCES ARRHYTHMOGENIC CALCIUM WAVES IN VENTRICULAR CARDIOMYOCYTES. Becker M. Al-khayatt , Markus B. Sikkel, Anita A. Laviada, Hung-Yen Ke, Christina Rowlands, Kenneth T. Macleod 3652-P os B oard #B380 AUTOMATED ACTION POTENTIAL RECORDING IN STEM CELL-DERIVED CARDIOMYOCYTES FOR PROARRHYTHMIA ASSESSMENT. Liudmila Polonchuk , Fabian Häusermann, Franz Schuler, Thomas Singer, Rubén Alvarez-Sanchez 3653-P os B oard #B381 COMPUTATIONAL INVESTIGATION INTO FEMALE SUSCEPTIBILITY TO AROUSAL INDUCED ARRHYTHMIAS IN LONG-QT SYNDROME TYPE 2. Pei-Chi Yang , Robert D. Harvey, Colleen E. Clancy 3654-P os B oard #B382 COMPUTATIONAL ANALYSIS OF EXTRACELLULAR CALCIUM EFFECT ON ACTION POTENTIAL DURATION. Elisa Passini , Stefano Severi 3655-P os B oard #B383 THE REDUCED REPOLARIZATION RESERVE ENHANCES THE LQT1 EFFECTS IN HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES: A SIMULATION STUDY. Michelangelo Paci, Jari Hyttinen , Stefano Severi 3656-P os B oard #B384 HOW “FUNNY” IS THE CARDIAC PACEMAKING? A QUANTITATIVE ANALYSIS BASED ON DYNAMIC CLAMP RECORDINGS. Enrico Ravagli, Annalisa Bucchi, Chiara Bartolucci, Mirko Baruscotti, Dario DiFrancesco, Stefano Severi 3657-P os B oard #B385 A MECHANISTIC ANALYSIS OF VARIABILITY BETWEEN VENTRICULAR CARDIOMYOCYTES. Ryan A. Devenyi , Eric A. Sobie Muscle Regulation (Boards #B386–#B410) 3658-P os B oard #B386 DCM MUTATIONS IN TROPOMYOSIN INDUCE LOSS OF THERMAL STABILITY WHEN THE MUTATION IS PRESENT IN A SINGLE CHAIN OF THE TM DIMER. Miro Janc, Michael A. Geeves 3659-P os B oard #B387 DISEASE CAUSING TROPONIN C MUTATIONS HAVE VARIED EFFECTS ON ACTIN REGULATORY STATES. Tamatha Baxley, Jose R. Pinto, Joseph M. Chalovich 3660-P os B oard #B388 TRUNCATION OF THE MOBILE DOMAIN OF CARDIAC TRO- PONIN I RESULTS IN BIPHASIC CALCIUM-DEPENDENT THIN FILAMENT ACTIVATION. Daniel C. Rieck , Zhiqun Zhou, King-Lun Li, R. John Solaro, Wen-ji Dong

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Biophysical Society 58 th Annual Meeting, San Francisco, California