BPS Program Book 2014

1707-P os B oard #B437 ACTIVATION AND SENSITIZATION OF THE CAPSAICIN RECEPTOR TRPV1 BY ALLYL ISOTHIOCYANATE. Yeranddy A. Alpizar, Maarten Gees, Brett Boonen, Alicia Sanchez, Bernd Nilius, Thomas Voets, Karel Talavera 1708-P os B oard #B438 MOLECULAR ADAPTATIONS TO EXTREME THERMOGENESIS IN MAMMALIAN HIBERNATORS. Willem J. Laursen , Owen Funk, Jena Goodman, Dana K. Merriman, Nicholas T. Ingolia, Sviatoslav N. Bagriantsev, Elena O. Gracheva  Ligand-gated Channels II (Boards #B439-#B466) 1709-P os B oard #B439 TRANSPORT OF ANTIBIOTICS THROUGH THE SUBSTRATE SPECIFIC OPRD CHANNEL OF PSEUDOMONAS AERUGINOSA. Susruta Samanta , Matteo Ceccarelli 1710-P os B oard #B440 EXPRESSION, PURIFICATION AND STABILIZATION OF THE MOUSE 5HT3 RECEPTOR. Gherici Hassaine, Cedric Deluz, Alexandra Graff, Christophe Moreau, Romain Wyss, Luigino Grasso, Aline Desmyter, Takashi Tomizaki, Xiao-Dan Li, Henning Stahlberg, Horst Vogel, Hugues Nury 1711-P os B oard #B441 SUBUNIT-DEPENDENT INHIBITION OF NEURONAL NICOTINIC ACETYLCHOLINE RECEPTORS BY PHILANTHOTOXINS. Hamid S. Kachel , Henrik Franzyk, Kristian Strømgaard, Denis B. Tikhonov, Ian R. Mellor 1712-P os B oard #B442 STUDIES ON FAST NACH RECEPTOR KINETICS UTILIZING A NEW APPROACHTO ULTRA-FAST COMPOUND APPLICATIONS IN AUTOMATED PATCH CLAMP. Timm Danker , Elke Guenther 1713-P os B oard #B443 ASYMMETRIC AGONIST SELECTIVITY OF AGONIST SITES IN ( α 4 β 2)2 α 4 NICOTINIC ACETYLCHOLINE RECEPTORS: A KEY DETERMINANT OF AGONIST EFFICACY. Simone Mazzaferro, Federica Gasparri, Karina New, Constanza Alcaino, Isabel Bermudez 1714-P os B oard #B444 LINEAR FREE ENERGY RELATIONSHIPS FOR NEUROTRANSMITTER BINDINGTO A NICOTINIC ACETYLCHOLINE RECEPTOR. Prasad Purohit , Shaweta Gupta, Iva Bruhova, Anthony Auerbach 1715-P os B oard #B445 ENERGY MAPS OF ACETYLCHOLINE RECEPTOR GAT- ING. Prasad Purohit, Shaweta Gupta, Snehal Jadey, Anthony Auerbach 1716-P os B oard #B446 GATING PHI VALUES IN THE MUSCLE ACETYLCHOLINE RECEPTOR α M2- α M3 LINKER WITH VS. WITHOUT AGONISTS. Shaweta Gupta , Anthony Auerbach 1717-P os B oard #B447 FUNCTIONAL ASYMMETRY OF AGONIST BINDING IN FETAL AND ADULT MUSCLE ACETYLCHOLINE RECEPTORS. Tapan K. Nayak , Shaweta Gupta, Anthony Auerbach 1718-P os B oard #B448 ACIDIC SIDE-CHAIN ROTAMERS AND THEIR IMPACT ON ION CONDUCTION THROUGH THE NICOTINIC ACETYLCHOLINE RECEPTOR. Tyler J. Harpole , Claudio Grosman

1719-P os

B oard #B449

education travel awardee

NEURONAL NICOTINIC ACETYLCHOLINE RECEPTORS: THE DEVELOPMENT OF METHODS FOR PRODUCING AFFINITY-PURIFIED AND LIPID-RECONSTITUTED RECEPTORS THAT RETAIN FUNCTIONALITY. Akash Pandhare , Steven Riela, Michaela Jansen, Michael P. Blanton 1720-P os B oard #B450 STOICHIOMETRY FOR ACTIVATION OF NEURONAL ALPHA7 NICOTINIC RECEPTORS. Natalia Andersen , Jeremias Corradi, Steven Sine, Cecilia B. Bouzat 1721-P os B oard #B451 PROGRESIVE ANALYSIS OF NACHR STABILITY IN THE LIPIDIC CUBIC PHASE: NACHR DETERGENT SOLUBILIZATION AND FRACTIONAL MOBILITY. Luis F. Padilla-Morales , Joel E. González Nieves, Claudia Lanauze, Carlos A. Báez-Págan, Orestes Quesada-González, Jose A. Lasalde-Dominicci 1722-P os B oard #B452 CALCULATION OF CHOLESTEROL BINDING AFFINITY FOR PENTAMERIC LIGAND-GATED ION CHANNELS. Reza Salari , Jerome Henin, Grace Brannigan 1723-P os B oard #B453 AGONIST RESPONSE INDUCED BY NICOTINIC ALPHA-7 AGONIST IS INHIBITED BY ANTIPSYCHOTIC DRUGS. Kristen Frederiksen , Maja Jessen, Jonatan Fullerton Støier, Kim Dekermendjian, John Paul Redrobe, Christoffer Bundgaard, Jørgen Calí Eskildsen, Jesper Frank Bastlund 1724-P os B oard #B454 THE ROLE OF THE FIFTH SUBUNIT ON SENSITIVITY OF α 4 β 2- CONTAINING NICOTINIC ACETYLCHOLINE RECEPTORS TO ALLOSTERIC MODULATORS. Constanza Alcaino 1725-P os B oard #B455 AN INTEGRATIVE MODEL OF THE PLEIOTROPIC EFFECTS OF GENISTEIN AND CYCLOSPORINE A IN FUNCTIONAL UPREGULATION OF ALPHA 7 NACHRS. Joseph Farley , Mohammad Faridul Islam, Patrick Beard Schwartz, Kristi DeBoeuf, Jed Rose 1726-P os B oard #B456 STRUCTURE FUNCTION STUDIES AT TWO DIFFERENT NICOTINIC ACETYLCHOLINE RECEPTOR SUBTYPES. Michael R. Post , Henry A. Lester, Dennis A. Dougherty 1727-P os B oard #B457 IDENTIFYINGMOTIFS ESSENTIAL FOR SELECTIVE ACTIVATION OF NICOTINIC ACETYLCHOLINE RECEPTORS. Christopher Marotta , Henry A. Lester, Dennis A. Dougherty 1728-P os B oard #B458 education travel awardee VOLATILE ANESTHETIC ISOFLURANE. David D. Mowrey , QiangLiu, Vasyl Bondarenko, Qiang Chen, Edom Seyoum, Yan Xu, Jie Wu, Pei Tang 1729-P os B oard #B459 INSIGHTS INTO THE DISTINCTLY DIFFERENT SENSITIVITIES OF α 7 AND α 7 β 2 NACHRS TO THE

M O N D A Y

FUNCTIONAL CHIMERAS OF THE HUMAN α 7 ACETYLCHOLINE RECEPTOR PROVIDE INSIGHTS INTO ALLOSTERIC MODULATION. Edom Seyoum , Tommy S. Tillman, Yan Xu, Pei Tang

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Biophysical Society 58 th Annual Meeting, San Francisco, California