AOAC SPADA February 2015 Meeting Book

Epizootic VEE Transmission

Primary Vector multiple mosquito species

h Ot er species naturally infected but not amplifiers

Vertebrate H t os : Horses

Dead-end hosts : Humans –epidemics of ’flu like illness, encephalitis

VEE - high viremia in horses – movement control is appropriate

Epizootic VEEV infections 

• Equine pathogen – In natural outbreaks, equine cases precede human • Equids are primary amplifier for human infections • Expect simultaneous impact in bioterrorism event • Human pathogen – Adults experience influenza‐like illness • Attack rate nearly 100% • 1‐5 day incubation, illness 1‐2 weeks • Malaise, spiking fever, rigors, severe headache,   photophobia, myalgia in legs and lumbosacral area • Nausea, vomiting, cough, sore throat, diarrhea