AOAC SPADA February 2015 Meeting Book

Epizootic VEEV infections (continued)  • Human pathogen (continued) – Neurologic manifestations in small percent of elderly  and children  • Neck stiffness, convulsions, coma, paralysis.  • Most VEE fatalities occur in children (up to 20%)

• Transmissible by aerosol – Human‐human transmission in natural  outbreak is negligible  – Virus is stable in aerosol form

C F t lit R t ase a a y a es

Equine

Human

WEE

20‐40%

~10%

EEE

~ 90%

~33%

VEE

38‐90% <1 – 20%*

* most VEE fatalities occur in children