Gynae BT 2017

Intro

Mission

Concept

Solution

Practice

Mathematical Description /Normalization - EQD2

➢ BED is the virtual dose value that produces the same biological effect as the physical dose with an infinite low dose rate

➢ Calculated BED values are normalized to conventional EBRT with 2 Gy / fraction (reference schedule) :

BED = D [ 1 + g  d / ( / ) ] = D 2Gy

[ 1 + 2 / ( / ) ]

g

➢ To calculate the total isoeffective dose D 2Gy

of a combined treatment, all

isoeffective doses D

are added up :

2Gy

D

= D

+ D

2Gy, TOTAL

2Gy, EXTERNAL

2Gy, BRACHY