Gynae BT 2017

Intro

Mission

Concept

Solution

Practice

Values of biological parameters • Tumour and early reacting normal tissue:

10 12 14 16 18 20 22 24 26 28 30

/ ~ 10 Gy

7 – 20 Gy for most tumours 9 – 10 Gy for cervix carcinoma

T

~ 1.5 hours

0.5 – 1.5 hours

1/2

• Late reacting normal tissue: EQD2 (Gy/fraction)

0 2 4 6 8

/ ~ 3 Gy

0.5 – 6 Gy 3 – 4 Gy for bladder, rectum, sigmoid 5 6 7 8 9 10

0

1

2

3

4

nominal Dose (Gy/fraction)

T

~ 1.5 hours

1 – 2 hours

1/2

Clinical and experimental experience