Gynae BT 2017
Next generation of clinical trials based on IGABT + IGRT as CCRT - Hypothesis driven - Comparative Trials on IGABT vs. 2D (randomized) Dose escalation for advanced disease HR CTV (LC, OS)
Dose de-escalation for limited and favourable
advanced disease (good response,…) (Morb/QoL)
Systematic Introduction of IMRT/IGRT (Morb/QoL
Para-aortic RT, SIB (Lymphnode) (NC, OS)
Systematic concomitant radiochemotherapy min. 5 cycl for subgroups with high risk of distant metastases (OS) Testing Dose/Volume constraints for Target and OARs Biomarker investigation (Hypoxia, HPV, EGFR) VEGF..)
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