Gynae BT 2017

PORTEC-1: risk factors for locoregional relapse

PORTEC Locoregional relapse

Treatment arm

FIGO review grade

30

30

N 354 360

F 15 50 P <.001

N 395 88 86 145

F 28 9

RT no RT Logrank

I II III ND Logrank

15 13 P =0.006

III

20

20

no RT

I II ND

10

10

RT

0

0

years

0

5

242 49 39 78 10

15

At risk: 395

I II III ND

323 74 52 111

64 9 5 12

years

0

5

199 209 10

15

88 86 145

At risk: 354 360

RT no RT

284 276

48 42

Invasion

Age

30

30

N 294 420

F 19 46 P =0.04

N 200 271 243

F 8

<1/2 >1/2 Logrank

<60 60-70 >70 Logrank

27 30 P =0.003

>70

20

20

>1/2

60-70

10

10

<1/2

<60

0

0

years

0

5

146 165 97 10

15

At risk: 200 271 243

years

0

5

179 229 10

15

<60 60-70 >70

182 211 167

32 41 17

At risk: 294 420

<1/2 >1/2

233 327

39 51

Creutzberg et al, ASTRO 2009, IJROBP 2011