Gynae BT 2017

PORTEC-4a trial design

➢ Molecular integrated vs standard indications for adjuvant treatment:

Randomisation

Standard treatment recommendation based on clinicopathological factors

Individual treatment recommendation based on molecular pathology analysis

1

2

Favourable Intermediate Unfavourable

Vaginal brachytherapy

Observation (~55%)

Vaginal brachytherapy (~40%)

External beam radiation therapy (~5%)

Follow-up and Quality of Life