Practice Update: Cardiology

CONTENTS 5

RESEARCH Editor’s picks 6 Significance of Subclinical Atrial Fibrillation in Older Patients 8 Optical Coherence Tomography Characterization of Coronary Lithoplasty for Treatment of Calcified Lesions 9 Association of Genetic Variants Related to Serum Calcium Levels With Coronary Artery Disease and Myocardial Infarction 10 Relationship of Alcohol Consumption to All-Cause, Cardiovascular, and Cancer-Related Mortality 11 Warfarin Use Is Associated With Progressive Coronary Arterial Calcification General cardiology 22 Bromocriptine Effective for the Treatment of Peripartum Cardiomyopathy 22 Antiplatelet Regimen for Patients With Breakthrough Strokes While on Aspirin Arrhythmias/heart rhythm disorders 23 3-Day Interruption of Direct Oral Anticoagulants Appropriate for Most Procedures 24 PAC or PVC on 12-Lead ECG May Predict Risk of Atrial Fibrillation, Heart Failure, or Death Cardiac procedures & surgery 26 Improved Outcomes With On- vs Off-Pump Coronary- Artery Bypass 27 Influence of Diabetes on Long-Term Coronary Artery Bypass Graft Patency Coronary heart disease 28 Coffee Consumption Associated With Reduced Mortality Risk

CONFERENCE 12 European Society of Cardiology Congress 2017 COVER 6 Significance of Subclinical Atrial Fibrillation in Older Patients

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12 ESC 2017: The Gender Gap in Death from Acute Myocardial Infarction Is Closing, Particularly in Women Younger Than Age 60 13 ESC 2017: Ablation of Atrial Fibrillation Improves Quality of Life More than Drugs – CAPTAF Trial 14 ESC 2017: Catheter Ablation Improves Outcomes in Patients With Heart Failure and Atrial Fibrillation – CASTLE-AF Trial 16 ESC 2017: The Interleukin-1 β Inhibitor Canakinumab Cuts Cardiovascular Disease and Lung Cancer Risk by Reducing Inflammation – CANTOS Trial 18 ESC 2017: Renal Denervation Lowers Blood Pressure in Hypertensive Patients Not Taking Antihypertensive Medication – SPYRAL HTN-OFF MED Trial 20 ESC 2017: Two Results of the PURE Study May Be Game Changers in Heart Disease Prevention 20 ESC 2017: Apixaban Lowers Stroke Risk in Patients Undergoing Cardioversion for Atrial Fibrillation – EMANATE Trial

FEATURES 29 My Approach to the Risk Stratification of Patients for Sudden Cardiac Death 30 My Approach to the Athlete With Wolff- Parkinson-White Syndrome (WPW)

PracticeUpdate Cardiology is published by Elsevier Australia ISSN 2206-4672 (Print) ISSN 2208-0228 (Online)

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VOL. 2 • NO. 2 • 2017