AROI-ESTRO GYN Teaching Course
A Phase II Randomized Trial Comparing Intensity Modulated Radiation Therapy
(IMRT) with Conventional Radiation Therapy in Stage IIB Carcinoma Cervix
(NCT00193804/TMH/158/2004): November 2004
Carcinoma Cervix Stage IIB (SQ / Adeno CA)
100 patients IMRT Pelvis (50 Gy/25#) + ICA – HDR (7 Gy x 5#) with Concomitant Chemo-radiation
100 patients Conventional External RT (40 Gy /20#) + ICA – HDR (7 Gy x 5#) with Concomitant Chemo-radiation
HYPOTHESIS:
• Reduction in Acute and Late RT toxicity’s by:15-25%
• Accrual Period: 5 years
• Power of detection: 80% (alpha error: 0.05)
Final Analyses: Ongoing
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