AROI-ESTRO GYN Teaching Course

TMH Study; ASTRO 2014

• Daily CBCT IGRT

• Cervical cancer with intact Uterus

• Nodal CTV matching

• N = 40 patients with FIGO IIB-IIIB

• Mid RT Tumor Regression with MRI

• Tumor regression: the mean cervical tumor

Surrogate for Organ Motion : Online – Offline

volume reduced from 58.4 cc at diagnosis to

matching (Intrafraction)

28.3 cc) at mid treatment

Mean X

Mean Y

Mean Z

Lateral (mm)

ANT-POST

SUP-INF (mm)

Parameter

Error (in mm) measured along

(mm)

X-Axis

Y-axis

Z-axis

Day 5

5.3

7.9

6.4

(RT – LT )

(ANT-POST)

(SUP-INF)

Day 10

4.9

7.8

7.6

SD of Random error (σ) SD of systematic error (ξ)

4.3

5.8

6.6

Day 15

4.7

8.8

7.2

Day 20

6.4

7.5

8.7

2.2

2.6

3.4

Day 25

4.7

7

9.6