AROI-ESTRO GYN Teaching Course
TMH Study; ASTRO 2014
• Daily CBCT IGRT
• Cervical cancer with intact Uterus
• Nodal CTV matching
• N = 40 patients with FIGO IIB-IIIB
• Mid RT Tumor Regression with MRI
• Tumor regression: the mean cervical tumor
Surrogate for Organ Motion : Online – Offline
volume reduced from 58.4 cc at diagnosis to
matching (Intrafraction)
28.3 cc) at mid treatment
Mean X
Mean Y
Mean Z
Lateral (mm)
ANT-POST
SUP-INF (mm)
Parameter
Error (in mm) measured along
(mm)
X-Axis
Y-axis
Z-axis
Day 5
5.3
7.9
6.4
(RT – LT )
(ANT-POST)
(SUP-INF)
Day 10
4.9
7.8
7.6
SD of Random error (σ) SD of systematic error (ξ)
4.3
5.8
6.6
Day 15
4.7
8.8
7.2
Day 20
6.4
7.5
8.7
2.2
2.6
3.4
Day 25
4.7
7
9.6
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