AROI-ESTRO GYN Teaching Course

Phase III RCT of Postoperative Adjuvant Conventional Radiation (3DCRT) Vs. Image Guided Intensity Modulated Radiotherapy (IG-IMRT) for Reducing Late Bowel Toxicity in Cervical Cancer (PARCER): Interim Analysis (Tata Memorial Centre)

Post Hysterectomy Needs Adjuvant RT

Hypothesis: IMRT will significantly reduce grade ≥ II late bowel toxicity with postoperative radiation

Stratified Randomization Type of Hysterectomy Use of Concurrent Chemotherapy

N=120 Standard RT

N=120 IG-IMRT (Tomotherapy)

CTCAE version 3.0, QOL (EORTC QLQ C30 & Cx-24 )

Interim Analysis Planned : 50% complete F/up of 18 mths.