AOAC OMB Final Action Recommendation (December 2019)-2016.14

ERP SUMMARY FOR FIRST TO FINAL ACTION METHOD RECOMMENDATION

AOAC OMA# 2016.14 - FOS (Fructans) in Infant and Adult Nutritionals

GUIDANCE FOR AOAC ERPS - APPENDIX G 1 Considered? Comments/Reference if applicable MethodApplicability YES This method is suitable for the determination of fructans in infant formula ERP First Action to Final Action recommendations & improvements YES No additional recommendations or improvements required Draft Final Action method reviewed by ERP YES Via e-Ballot (November 2019) Safety Concerns YES Noted ReferenceMaterials YES NIST SRM 1849a Single Laboratory Validation YES Journal of AOAC INTERNATIONAL VOL. 98, NO. 1038, 2015 Journal of AOAC INTERNATIONAL VOL. 100, NO. 753, 2017 Reproducibility/Uncertaintyand Probability of Detection YES Comparison to SMPR ( SMPR criteria met?) YES Feedback from Users of Method YES

DOCUMENTATION Safety Evaluation ReferenceMaterials

Available?

Comments

YES YES YES YES YES YES YES YES NO YES YES

In ERP Reviews in Review Book

Yes, NIST materials and SPIFAN matrices Yes, published as AOAC 2016.14 Published as OMA, Appendix L Part of ERP Review and Discussions First Action published as AOAC 2016.14

SLV or PTM

Approved Validation Protocols

Statistics Review

Method Published in OMA

Method Performance vs SMPR criteria

SMPR 2014.002

Feedback Information

Addressed as part of ERP discussions and in SPIFAN

Additional Recognition(s)

ERP Reports

ERP Reports available in review book J. AOAC Int. 100, 753(2017); J. AOAC Int. 98, 1038(2015)

Manuscript(s) Published in JAOAC

ERP Method Recommendation (Final Action/Repeal/Continuation)

1 Official Methods of Analysis of AOAC INTERNATIONAL , Appendix G: Procedures and Guidelines for the Use of AOAC Voluntary Consensus Standards to Evaluate Characteristics of a Method of Analysis, p.3 “ First Action to Final Action Methods: Guidance for AOAC Expert Review Panels.”