Biophysical Society Thematic Meeting| Lima 2019

Revisiting the Central Dogma of Molecular Biology at the Single-Molecule Level

Speaker Abstracts

16:45 - 17:00

Christian Kaiser, Johns Hopkins University, USA * The Ribosome Cooperates with Chaperones to Guide Multidomain Protein Folding Scott Blanchard, Weill Cornell Medicine, USA * Endogenous Ribosomal RNA Sequence Variation Can Modulate Stress Response Gene Expression and Phenotype Ruben Gonzalez, Columbia University, USA Ribosomes in Action: The Role of Dynamics in the Mechanism and Regulation of Translation

17:00 - 17:15

17:15 - 18:00

Saturday, July 20, 2019 8:30 – 18:00

Auditorium Entrance, 1 st Floor

Registration/Information

Session VI

Protein Folding and Allostery Piere Rodriguez-Aliaga, Stanford University, USA, Chair Matthias Rief, Technische Universität München, Germany Single Molecule Mechanics of Protein Folding and Binding

9:00 - 9:45

9:45 - 10:15

Rodrigo Maillard, Georgetown University, USA Activation of a Protein Kinase via Asymmetric Allosteric Coupling of Structurally Conserved Signaling Modules

10:15 - 10:45

Mauricio Baez, University of Chile, Chile Folding Free Energy Barriers of Topologically Knotted Proteins

Foyer, 1 st Floor

10:45 - 11:15

Coffee Break

Session VII

Protein Processing Machines Rodrigo Maillard, Georgetown University, USA, Chair

11:15 - 11:45

Christian A.M. Wilson, University of Chile, Chile Studying the Mechanical Properties of Protein Translocation by Optical Tweezers and Nanorheology Piere Rodriguez-Aliaga, Stanford University, USA A Finely Tuned Molecular Motor: Mechanochemistry and Power Efficiency in the AAA+ Protease Machine ClpXP Erik Jonsson, University of California, Berkeley, USA * Direct Observation of Substrate Translocation and Conformational Dynamics in the 26s Proteasome

11:45 - 12:15

12:15 - 12:30

12:30 - 12:45

Gabriel Lander, The Scripps Research Institute, USA * Mechanisms of Mitochondrial Machines of Mass Destruction

12:45 - 14:45

Lunch ( on own)

14:45 - 16:00

Free Time

Foyer, 1 st Floor

16:00 - 16:30

Coffee Break

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