Biophysical Society Thematic Meeting| Lima 2019

Revisiting the Central Dogma of Molecular Biology at the Single-Molecule Level

Speaker Abstracts

Session VIII

Nucleic Acids Machines Eli Rothenberg, New York University, USA, Chair

16:30 - 16:45

Wei Ting (Chelsea) Lee, New York University, USA * Superresolution Imaging of Replication-associated G4 DNA in Human Cells Nikos Hatzakis, University of Copenhagen, Denmark * Direct Observation of CRISPR-Cas12 as Conformational Sampling Reveals How Conformational Activation Promotes Catalysis and Resetting of the Endonuclease Activity Ian Nova, University of Washington, USA * Detecting Single Steps During Transcription and a Half-translocated Pause Complex of E. coli RNA Polymerase Using Nanopore Tweezers Michelle Wang, Cornell University, USA Molecular Highways – Torsional Consequences of DNA Motor Proteins

16:45 - 17:00

17:00 - 17:15

17:15 - 18:00

19:30

Banquet

Damajuana Restaurant

Sunday, July 21, 2019 8:30 – 12:30

Auditorium Entrance, 1 st Floor

Registration/Information

Session IX

Extracting Kinetics from Molecular Processes Mauricio Baez, University of Chile, Chile, Chair

9:00 – 9:45

Gijs Wuite, Vrije Universiteit Amsterdam, the Netherlands – Jubilee Lecturer Single Molecule Manipulation and Imaging of Complex DNA-Protein Transactions

9:45 – 10:15

Olga Dudko, University of California, San Diego, USA Mechanical Fingerprints of Biomolecules, Decoded

10:15 - 10:30

Sara Tafoya, LUMICKS, USA * Using a System’s Equilibrium Behavior to Reduce Its Energy Dissipation in Non- Equilibrium Processes

Foyer, 1 st Floor

10:30 - 11:00

Coffee Break

Session X

Nanoscale Imaging of Cellular Processes III Tomas Kirchhausen, Harvard University, USA, Chair

11:00 - 11:30

Eli Rothenberg, New York University, USA A Single-Molecule View of Mammalian DNA Double-strand Break Repair Xiaowei Zhuang, Harvard University, USA – Jubilee Lecturer Imaging at the Genomic-scale: From 3D Organization of the Genomic DNA to Cell Atlas of Complex Tissues

11:30 - 12:15

12:15 - 12:30

Carlos Bustamante, University of California, Berkeley, USA Closing Remarks and Biophysical Journal Poster Awards

*Short talks selected from among submitted abstracts

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