Biophysical Society Thematic Meeting| Lima 2019

Revisiting the Central Dogma of Molecular Biology at the Single-Molecule Level

Welcome Letter

July 2019

Dear Colleagues, We would like to welcome you to the Biophysical Society Thematic Meeting titled, Revisiting the Central Dogma of Molecular Biology at the Single-Molecule Level . We have assembled a stimulating program, with lectures focused on how recent discoveries by single-molecule manipulation and nanoscale imaging enable molecular level understanding of key molecular processes involved in the central dogma of molecular biology. The research done at the single-molecule level is inherently interdisciplinary, taking place at the interface of cell biology, physics, biochemistry, and computational biology. This meeting will bring together researchers with a wide range of expertise and interests who use single-molecule tools to address problems in each of these fields. Particular aspects that will be covered by the meeting will include replication, transcription, DNA repair, protein synthesis, chaperone-mediated protein folding/degradation, and molecular motors. In addition, the goal is to feature the latest cutting-edge developments in single-molecule instrumentation and nanoscale visualization, and steered molecular dynamics simulations. We hope that the meeting will promote discussions and foster future interdisciplinary collaborations. The approximately 150 attendees to this conference will enjoy a full program with 34 lectures, 59 posters, and 20 flash talks, bringing together well recognized scientists from different fields and 15 countries, promising a truly international and multidisciplinary inspiring environment. In addition, we will have two social events where the participants can expand their social networks and meet researchers from different parts of the globe. We encourage you to enjoy the different social/cultural activities that Lima has to offer as the gastronomic and cultural capital of South America. Particularly, we invite you to experience the diversity and richness of the world-renowned Peruvian cuisine, and to visit the world-heritage sites from pre-Columbian, Inka empire, and Spanish colonial eras located in multiple parts of the city. We would like to thank our sponsors University of Engineering and Technology (UTEC), National Science Foundation (NSF), Instituto Nacional de Salud (INS), IUPAB, CONCYTEC, Oxford Nanoimaging (ONI), Zeiss, IUBMB, Beckman Coulter, ACS Publications, Chroma, Lumicks, and the Chilean Society of Biochemistry for supporting this Thematic Meeting. Thank you all for joining our meeting, and we look forward to having a great four-day event together! Sincerely yours, Carlos Bustamante — University of California at Berkeley, USA Daniel Guerra — Cayetano Heredia University, Peru Victoria Guixé — University of Chile Rodrigo Maillard — Georgetown University, USA

Edward Málaga-Trillo — Cayetano Heredia University, Peru Lía Pietrasanta — University of Buenos Aires, Argentina Piere Rodriguez Aliaga — Stanford University, USA Julio Valdivia — Universidad de Ingeniería y Tecnología (UTEC), Peru Christian A.M. Wilson — University of Chile