Upper GI 2017

State of art of radiation therapy in Esophageal Cancer

 Preoperative Chemoradiation  Planned Esophagectomy • Walsh et al – 1996 (Trimodality)

SVV Benefit

• POET - 2009 (Trimodality) • FFCD 9901 - 2014 (Trimodality) • Urba et al – 2001 (Trimodality) • Burmeister et al – 2005 (Trimodality) • Tepper et al – 2008 (Trimodality)

NO SVV Benefit

NO SVV Benefit

SVV Benefit

NO SVV Benefit

NO SVV Benefit

SVV Benefit

• CROSS - 2015 (Trimodality)

 Definitive Chemoradiation  Salvage Esophagectomy • RTOG 85-01 - 1999

SVV Benefit

• INT 0123 - 2002

NO SVV Benefit

 Chemoradiation  or Selective Esophagectomy

NO SVV Benefit NO SVV Benefit

• FFCD 9102 - 2015 • ESSEN Trial - 2005