Upper GI 2017

 Preoperative Chemoradiation  Planned Esophagectomy

 Preoperative Chemoradiation  Planned Esophagectomy

N. Histology

EQD2

pCR

28 % 25 % 16 % 40 % 33 % 29 %

• Walsh et al – 1996

113 pts Adeno 100%

EQD2: 42.33 Gy

100 pts Adeno 75% EQD2: 48.75 Gy

• Urba et al – 2001

256 pts Adeno 62% EQD2: 36.17 Gy

• Burmeister et al – 2005

56 pts Adeno 75%

EQD2: 49.56 Gy

• Tepper et al – 2008

• FFCD 9901 – 2014

194 pts Adeno 29% EQD2: 44.25Gy

• CROSS - 2015

366 pts Adeno 75% EQD2: 40.71 Gy

Mod from Cellini et al ; Radiat Oncol 2014 (Italy)