Upper GI 2017

Regression-Scores after neoadjuvant therapy

According to Becker et al:

Morphological regressions signs: • oedema • necrosis • foamy histiocytes

• fibrosis and hyalinosis

Grading of Histophathologic Regression in the Primary Tumor Bed

Grade

Description

1a 1b

No residual tumor / tumor bed < 10% residual tumor / tumor bed 10-50% residual tumor / tumor bed > 50% residual tumor / tumor bed

2 3

From: Becker et al. Ann Surg 2011 or Becker et al. Cancer 2003

Institute of Pathology | Alexander Quaas

Gastrointestinal Cancer Group Cologne (GCGC)