Upper GI 2017

 Preoperative Chemoradiation  Planned Esophagectomy

• POET - 2009 (Trimodality)

uT3-4NXM0

Siewert I-III= 100%

126 pts (326 planned)

Adeno 100%

NO SVV Benefit  Significant improvement of pCR (2 vs 15.6%; p=0.03) favoring RTCT

 Significant improvement of pN0 (36.7 vs 64.4%; p=0.03) favoring RTCT Stahl et al ; JCO – 2009 (Germany)