Upper GI 2017

 Preoperative Chemoradiation  Planned Esophagectomy

• CROSS - 2015 (Trimodality)

T1N1+T2-3N0-1M0

Junction= 24%

366 pts

Adeno 75%

Signif SVV Benefit

RTCT: 41.4 Gy (1.8 Gy fx) + Carbo/Paclitaxel

EQD2: 40.71 Gy

Van Hagen et al ; N Engl J Med 2012 Oppedijk et al; JCO 2014 Shapiro et al ; Lancet Oncol 2015

The Netherlands