Upper GI 2017

 Preoperative Chemoradiation  Planned Esophagectomy

 Preoperative Chemoradiation  Planned Esophagectomy

EQD2

Tumor site

N. Histology

Mid-Distal 79% 256 pts Adeno 62%

• Burmeister et al – 2005

EQD2: 36.17 Gy

Stage: T1–3, N0–1 M0

Stage: T1N1+T2-3N0-1M0

Junction 24% 366 pts Adeno 75% EQD2: 40.71 Gy

• CROSS - 2015

Statistically in favour of Preop ChemoRT

Mod from Cellini et al ; Radiat Oncol 2014 (Italy)