ISPAM Meeting Book September 18, 2016

PRESENTERS:

Scott Coates AOAC INTERNATIONAL

Scott Radcliffe Romer Labs

Erin Crowley Q Laboratories, Inc.

Brooke Schwartz Brooke Schwartz Consulting

Samuel Godefroy Université Laval

Kristen Spotz Grocery Manufacturers Association (GMA)

Markus Lacorn R-Biopharm

Jupiter Yeung Nestlé

Gregory Noonan US FDA

OBJECTIVES On Wednesday, March 16, 2016, the AOAC Research Institute held its Board of Directors meeting in conjunction with the AOAC Mid-Year meeting and discussed the direction of ISPAM. The decision was made to launch a working group to develop Standard Method Performance Requirements (SMPR®) for the detection of food allergens, which would include test kit applications for ELISA, PCR or other molecular based assays. AOAC held an Advisory Meeting comprised of food allergen thought leaders and experts toadvise and guide AOAC on the priority allergens and gaps in needed methodology for which ISPAM would develop voluntary consensus standards.

OUTCOMES

Introduction

AOAC INTERNATIONAL held an Advisory Panel meeting to discuss “Food Allergen” priorities on June 15, 2016. The AOAC International Stakeholder Panel on Alternative Methods (ISPAM) has undertaken the initiative to develop Standard Method Performance Requirements (SMPRs®) for food allergen assays. The working group is currently being formed and will officially launch in conjunction with the AOAC Annual Meeting & Exposition meeting on Sunday, September 18, 2016 in Dallas, TX USA. Priorities from this meeting will serve as the basis for the scope of the working group’s draft standard. Crowley provided an overview of ISPAM and its accomplishments to date. Coates provided a brief overview on the development of AOAC SMPRs®. Presentations were given by various panel members representing government, industry, and academia. These thought leaders addressed the current state of food allergen methodology, government regulations, progress on other international efforts, state of available technology, and gaps in needed methodology. Schwartz also provided a summary of various emerging technologies for the detection of food allergens.

Prioritization

Godefroy led the panel through a prioritization session that began with establishing criteria focused on targets where there are differences or discrepancies in methodology. The panel focused on two primary points of consideration for method needs: allergen targets and technologies. It was agreed that matrices would not be addressed during this discussion. The considerations for criteria included cost, time, and intersection of common food allergen regulations.

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