SPDS EXPERT REVIEW PANEL

2018 SMPR ERPs - METHOD REVIEW FORM

Submission ID

4105294197497655807

Submission Date

2018-08-19 18:10:19

AOAC Expert Review Panel: Method Review

Reviewer Information

Name

Tomasz Tuzimski

E-mail

tomasz.tuzimski@umlub.pl

Organization

Medical University of Lublin, Poland

Remember, the main purpose of your review is to ensure the method conforms to the applicable SMPR. View and download SMPRs here:

SPDS SMPRs SPSFAM SMPRs

Method Review

Title of Method

HPLC analysis of flavokavins and kavapyrones from Piper methysticum

AOAC Candidate Method Number (e.g. ALN-01)

AOAC Candidate Method KAV-004

Applicable SMPR

AOAC SMPR® 2018.005

I. Summary of the Method

A. Summary of the Method

The proposed method entitled ‘HPLC analysis of flavokavins and kavapyrones from Piper methysticum’ described by Meissner and Haberlein (et al.: Mathias Schmidt, Steffen Radtke, Gabriele Adis, Eva Maute, Katherina Kardos, and Janina Schnabel) is applicable for the detection and quantitation of the content of kavapyrones and flavokavains in dried, ground, kava roots prepared as an ethanolic extract. The developed method was evaluated following the definitions of AOAC SMPR 2018.005 with respect to Limit of Detection (LOD) and the Limit of Quantitation (LOQ), Linearity, Repeatability, Reproducibility, Recovery.

II. Review of the Method Only: