SPDS EXPERT REVIEW PANEL

A. Does the applicability of the method support the applicability of the SMPR? If not, please explain what is missing. B. Does the analytical technique(s) used in the method meet the SMPR? If not, please specify how it differs from what is stated in the SMPR. C. Are the definitions specified in the SMPR used and applied appropriately in the method? If no, please indicate how the terms are used. D. Does the method, as written, contain all appropriate precautions and warnings related to the method's reagents, components, instrumentation, or method steps that may be hazardous? If no, please suggest wording or option(s). A. Are the definitions specified in the SMPR used and applied appropriately in the supporting documentation (manuscripts, method studies, etc...)? If not, please explain the differences and if the method is impacted by the difference. B. Is there information demonstrating that the method meets the SMPR Method Performance Requirements using the Reference Materials stated in the SMPR? If not, then specify what is missing and how this impacts demonstration of performance of the method.

No, the applicability of the method support partially of the applicability of the SMPR.

Yes, The analytical technique used in the method meet the SMPR.

No, the definition of the SMPR requires the aerial part of Scutellaria baicalensis, but it is not in the proposed method.

No, It is suggested to reference SDS/MSDS database for the chemical used.

III. Review of Information in Support of the Method

No, the proposed method does not define well for the testing samples.

No, The botanical reference materials are not well defined in the proposed method.