SPDS EXPERT REVIEW PANEL

AOAC Candidate Method #KAV-002 HPLC Analysis Method Development for Kavalactones and Flavokavains in Kava Extract

Author(s): YijnTang and Chris Fiends Submitted by: Chris Fields, Applied Food Sciences

Method applicability:This is an UPLC-UVmethod for detection and quantification of the six major kavalactones (kavain, dihydrokavain, methysticin, dihydromethysticin, yangonin and desmethoxyyangonin) and three flavokavains (flavokavain A, flavokavain B, and flavokavain) C in kava raw materials (Piper methysticum Forst. F.), dietary ingredients and dietary supplement products. The method is applicable for analysis in the following matrixes: Piper methysticum roots, Tincture, Liquid phytocaps, capsules.

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Submitter notes: Applied Foods would like to be part of the multi-lab validation study independent if our method of analysis is chosen.

Primary reviewer: ‘•‡’Š Š‘—ǡ —•Š‹‡˜‹ŽŽ‡ Secondary Reviewer: Michael Chan, BCIT