SPADA Working Groups ~ April Meeting Book
STAKEHOLDER PANEL ON Agent Detection Assays Background & Fitness for Purpose Staphylococcal enterotoxin B
Sandra Tallent, PhD h b l Researc Micro io ogist US FDA AOAC Rockville, MD February 3, 2015
Background on Staphylococcal enterotoxins • Pyrogenic exoproteins • Stable proteins – Water soluble – Heat resistant – Protease resistant – Tolerate extreme pH changes • Twenty‐three homologous serologically distinct SEs identified • SEA‐SEE select agent status • Superantigenic
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