SPADA Working Groups ~ April Meeting Book

AOAC Stakeholder Panel on Agent Detection Assays: Stakeholder Panel Meeting

Meeting Minutes Thursday, March 10, 2015; 2:00 p.m. – 3:00 p.m. EST

Attendees

Panel Members (Present during all or part of the meeting) : Eileen Ostlund, USDA (Chair) Linda Beck, Naval Surface Warfare Center Ryan Cahall, Censeo Insight Joan Gebhardt, NMRC Pejman Naraghi-Arani, LLNL

AOAC Staff (Present during all or part of the meeting) :

Scott Coates Christopher Dent Krystyna McIver

Ann Powers, CDC Darci Smith, SRI

Meeting Minutes

I.

Welcome and Introductions

All participants were welcomed and roll call was taken.

II.

Review of Last Meeting and Fitness for Purpose Statement

Coates reviewed the Fitness for Purpose statement and explained that it had led him to draft SMPRs for VEE and EEV. EEV SMPR is for identification of EEV, WEE and VEE. The VEE-only SMPR is for confirmation methods. For identification methods Probability of Identification (POI) is used instead of Probability of Detection (POD). It would challenge the method with a number of viruses to determine when VEE is there and when it is not. Coates then asked the group for ideas on the best approach for proceeding with SMPRs for VEE/EEV. Group members said that it would be a great deal of time and effort to take a combined approach. DoD representatives advised that they would be satisfied with one just for VE E – even that alone is complex. Ostlund agreed and stated that the group will focus on an SMPR for VEE only, with the potential to look at the others once VEE is complete. The group then discussed development of SMPRs for identification, detection, or both. The primary need is to know which strain of the virus is present, so the initial focus will be on identification of VEE. Cahall advised that non pathogenic strains are of little interest.

III.

SMPR Development

The group proceeded to modify a draft SMPR. Since the scope is limited to VEE, WEE and EEE were removed.