PracticeUpdate: Neurology - Winter 2018

CONTENTS 3

EDITOR’S PICKS 5 Emergency Department Neuroimaging for Red Flag Findings in Children With Headaches

COVER 9 Effect of Modified Atkins Diet in Adults With Drug-Resistant Focal Epilepsy Comment by Amal Satte MD

EXPERT OPINION 12 Cerebral Blood Flow Changes After Radiation Therapy Identifies Pseudoprogression in Diffuse Intrinsic

6 MRI-Guided Thrombolysis for Stroke With Unknown Time of Onset 7 The Diagnostic Dilemma of Traumatic Lumbar Puncture 7 CNS-LCH: Common Hematopoietic Origin For LCH-Associated Neurodegeneration and Mass Lesions 8 α-Linolenic Acid is Associated With MRI Activity in Multiple Sclerosis 8 Restarting Antiplatelet Therapy After Spontaneous Intracerebral Hemorrhage 9 Effect of Modified Atkins Diet in Adults With Drug-Resistant Focal Epilepsy Comment by Amal Satte MD 10 Functional Neurological Disorders in Parkinson’s Disease 10 Encephalitis With mGluR5 Antibodies

Pontine Gliomas By John Laterra MD 13

Ultrasound and MRI Both Detect Increased Intracranial Pressure to Complement Comprehensive Workup By Michael A. Williams MD

CONFERENCE 14 Australian & New Zealand Association of Neurologists Annual Scientific Meeting 2018 By the PracticeUpdate Editorial Team

20 International Congress on Neuromuscular Diseases 2018 By the PracticeUpdate Editorial Team

© TIRZA/www.tirza.at

14 CTA Spot Sign Fails to Predict Expansion of Spontaneous Intracerebral Hemorrhage 15 Better Screening for Atrial Fibrillation Needed in Patients Who Present With TIA/Stroke 16 Perampanel Demonstrates Sustained Long-Term Efficacy Against Secondarily Generalized Seizures and Safety in Idiopathic Generalized Epilepsy 18 Efficacy of Alemtuzumab for Active RRMS is Maintained for 7 Years, in the Absence of Continuous Treatment

20 Transcranial Magnetic Stimulation Can Help Diagnose and Prognose Children With Sequelae of Acute Transverse Myelitis 21 Ultrasonography Valuable in Confirmation of Carpal Tunnel Syndrome 22 Significant Progress Has Been Made in Immune-Mediated Neuropathies 23 Protein Biomarkers of Dysferlinopathy Identified 24 Next-Generation Sequencing Can Be Helpful in Diagnosing and Characterizing Limb Girdle Muscular Dystrophy 26 Immune Globulins Continue to Be the Most Effective Treatment for Multifocal Motor Neuropathy

VOL. 3 • NO. 3 • 2018