TNM Staging of Head and Neck Cancer and Neck Dissection Classification

studied area. EGFR overexpression has been shown to be related to more advanced tumor stage and nodal stage, as well as worse prognosis in terms of locoregional control and overall survival. As a result, numerous compounds are under investigation to evaluate their effect on progression of disease. The most widely studied compound in the treatment of head and neck cancer is cetuximab, a monoclonal antibody that inhibits the EGFR. The use of biologic agents in head and neck cancer is an area of many ongoing research efforts.

10 TNM Staging of Head and Neck Cancer and Neck Dissection Classification