EBRO 2017

Main features of the management of women carrying a

BRCA1 or BRCA2 germline mutation

Annual breast screening with mammography, ultrasonography, and MRI, beginning at age 30

Prophylactic surgery •

oophorectomy recommended between at age 40 when BRCA1 mutation and delayed if BRCA2 mutation • mastectomy is an option which must be discussed at 30 yrs or latter (but not too late)

Medical prevention (still in clinical trials) •

Anti-estrogenes such as aromatase inhibitors after menopauses