EBRO 2017

Prophylactic mastectomy

• The resultant lack of knowledge drives and sustains patient anxiety, sometimes prompting them to select mastectomy in hopes of a cure while sacrificing cosmesis, body image, and perhaps sexuality • Kiebert GM, et al, J Clin Oncol. 1991 • Schover LR.CA Cancer Journal for Clinicians. 1991 • BRCA1/2 mutation carriers who underwent prophylactic mastectomy reported a less favorable body image, while 70% of them reported changes in their sexual relationships. • Van Oostrom I, et al. Long-term psychological impact of carrying a BRCA1/2 mutation and prophylactic surgery: a 5-year follow-up study. Journal of Clinical Oncology.2003