EBRO 2017

Association of risk reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality Domchek et al. JAMA, 2010

Prospective, multicenter cohort study of 2482 women BRCA1/2 mutation carriers ascertained between 1974 and 2008 and followed up until December 2009

Control group with no prophylactic mastectomy underwent mammography and MRI surveillance (until 50 yrs in the UK).

Mean follow up: 4 yrs

Domchek et al, 2010