EBRO 2017

Protective effect of oophorectomy on the breast cancer risk

BRCA1 No previous

BRCA2 No previous

BRCA1 Previous breast T N = 397

BRCA2 Previous breast T N =250

breast T N = 869

breast T N = 501

Oophorectomy Breast T

236 32 (13.6%)

100 7 (7.0%)

138 19 (13.8%)

70 4 (5.7%)

No oophorectomy Breast T

633 129 (20.4%)

401 94 (23.4%)

259 46 (17.8%)

180 14 (7.8%)

Domchek et al, 2010