Course book Advanced Treatment Planning 2018
Parameters for clinical outcome: Rectum
Dose-Volume limits for > G2 rectal toxicity with LQ corrected doses ( / = 3 Gy)
100
80
CTCAE G2 : Symptoms not interfering with ADL; medical intervention indicated RTOG G2 : Increase of 4-6 stools/day, or nocturnal stools, or moderate cramping
V50
60
V60
40
V65
Volume [%]
V70
V75
20
0
10
20
30
40
50
60
70
80
90
LQ equivalent dose in 2 Gy fractions (Gy)
Michalski JM et al. Radiation Dose-Volume effects in radiation-induced rectal injury. Int. J. Radiation Oncology Biol. Phys., Vol. 76, No. 3, Supplement, pp. S123–S129, 2010.
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