Course book Advanced Treatment Planning 2018
Parameters for clinical outcome: Rectum
Multivariate modeling for detecting rectal toxicity (G3 late rectal bleeding)
Surgery+ TD
50 = 82,5 Gy < Surgery- TD 50
= 91,7 Gy
Isoeffective TD
50 is 11% lower for Surgery+
n
n :
0.046
TD
: 82.5 Gy
1
1
50
=
n Dv
EUD
TD
: 93.1 Gy
NTCP
=
;
Logistic regression:
50
i
i
k
50 EUD TD
k :
10.4
TD
: 91.7 Gy
i
50
1
+
T Rancati et al. Inclusion of clinical risk factors into NTCP modeling of late rectal toxicity after high dose radiotherapy for prostate cancer. Radiother Oncol 100 (2011) 124–130.
Made with FlippingBook - Online Brochure Maker