Cervix BT - 2016

Limitations of the EQD2 model for BT

 Chemotherapy is not taken into account  Uncertainty increases for single fraction dose values >10Gy  Only cell repair is considered  α/β values and T 1/2  dose and dose rate inhomogeneity within BT volume is not considered  Overall uncertainty of the biological dose calculation (values) in the range of ~10% -> Reasonable rounding of values are under discussion (E.g. tumour type prostate, OAR etc.)

BT-GYN Teaching Course

D. Berger