Molecular Imaging 2017

Amino Acid Imaging (MET/FET)

Principle:

Disadvantages:

Binding reflects amino acid (i.e. methionine) transport

• Limited usefulness outside brain • Fusion with MRI/CT mandatory • Very limited availability ([ 11 C]methionine)

Advantages:

• High tumor/background ratio (in brain) •Independent from BBB disturbance • Relatively specific for malignancies • [ 123 I]-IMT SPECT widely available