Brain 17 Vienna

How to choose the best AED

1. Carbamazepine CBZ 2. Gabapentin GBP 3. Lacosamide LAC 4. Lamotrigine LTG 5. Levetiracetam LEV 6. Oxcarbazepine OXC 7. Perampanel PER 8. Phenobarbital Pb 9. Primidon PRM 10. Phenytoin PHT 11. Pregabalin PGB 12. Topiramate TPM 13. Valproic acid VPA 14. Zonisamide ZON

Time from randomization (years)

„time to treatment failure“: LTG > CBZ, GBP und TPM

Marson et al., Lancet 2007

„seizure control“ LEV = CBZ

Brodie et al., Neurology 2007