Brain 17 Vienna

Old AED: pros and cons

Phenobarbital

Sedation, allergic reactions Enzyme induction (cytochrome P450) Vertigo, allergic reactions, liver enzymes  , gingival hyperplasia, cerebellar degeneration Enzyme induction (cytochrome P450) Vertigo, Nausea, Ataxia, low blood sodium, nystagmus, allergic reactions, Enzyme induction (cytochrome P450) Tremor, gain of weight, coagulation disorders, thrombopenia, teratogenicity Enzyme inhibition

Phenytoin

Carbamazepine

Valproic acid