AOAC-03 Preliminary Program

• Sean Austin, Nestlé A New Analytical Method for the Determination of Inulin/FOS – a Dual Lab Validation • Heidi Evenocheck, AMWAY Short Chain (DP<10) Carbohydrate Analysis • Paula Trumbo, U.S. Food and Drug Administration Carbohydrate Labeling Update in Food and Supplement Products TDRM Symposium: How to Compare a Certified Value with an Analytical Result and How to Estimate Measurement Uncertainty (MU) Measurement uncertainty (MU) is a parameter associated with all measurement results and provides a quantitative indication of the quality of a measurement result. A realistic estimation of MU is an important part of method development and method validation. A well-developed understanding of the major sources of uncertainty even provides possibilities for further method optimization. Sometimes it is perceived that the estimation of MU of an analytical result is a complicated and difficult process. In addition, customers of analytical results do not know what to make of the “uncertainty”. Firstly, the symposium aims to describe how MU was implemented in European measurement laboratories over the past three decades with a lecture describing a European laboratory perspective. Thereafter different aspects of measurement uncertainty in relation to certified reference materials, proficiency testing and uncertainty of identity of components (e.g. botanicals) will be described. Different strategies for estimation of MU will be explained as well as the use of MU in relation to certified reference materials (CRMs). When is an analytical result in agreement with the certified value and when is it not? Likewise, in proficiency testing (PT) what is the difference between z-scores and zeta-scores? As will be discussed all such benchmarking requires realistic estimations of MU. CO-CHAIR: Håkan Emteborg, European Commission - JRC - IRMM CO-CHAIR: Donna Zink, AIM Research Enterprises • Máire Walsh The Role of MU in Ensuring Comparability and Traceability of Analytical Data: A European Laboratory Perspective • Håkan Emteborg, European Commission - JRC - IRMM Approaches to Estimate Measurement Uncertainty (MU) and how is MU Related to Certified Reference Materials? • Jörg Stroka, European Commission - JRC - IRMM Uses of Uncertainty Estimations in the European Reference Laboratory for Mycotoxins • James Harnly, U.S. Department of Agriculture Uncertainty of Identity in Botanicals

I Know what you Ate and where it Came from! Whole Genome Sequencing (WGS) is becoming a powerful and informative technology for the identification and characterization of food-borne pathogens—dramatically reducing analytical time and allowing for the resolution of thousands of species and serotypes of bacteria in a single test. Its applications are numerous from strain characterization to outbreak tracking and monitoring of microbial flora in diverse environments. Currently thousands of organisms are being sequenced in areas of the globe, and their data stored. How are we addressing the validation of these new technologies/methods that allow for the resolution of thousands of species and serotypes of bacteria using a single test? What does WGS means to the food industry and how can they take benefit of this technology? What is the added value in food (related outbreak tracking? In this Symposium, attendees will be: 1. Informed of the on-going work for standardization in the collection of volumes of meta-genomic data being generated; 2. Invited to participate in a round table discussion with speakers, discussing gaps in requirements and considerations necessary in the approaches that might be used by regulatory authorities to determine validation requirements of methods using these new technologies TDLM Symposium: Strategies for Internal Audits—Effective, Efficient, Economical Effective internal audits are a key component of an effective ISO 17025 management system. The standard is not specific about how an audit takes place; just that all aspects of the system are audited. The requirements of the standard will be described briefly. Then the symposium will focus on a number of approaches used for different types of audits. Each section will be shown in the context of a 17025-compliant internal auditing system. What the auditor should look for, objective evidence, procedures, policies will be described. The symposium will present various approaches to audits that ensure you get the most from your audit program. Approaches and techniques will be presented. These terms and audit “jargon” will be explained and the specific audit techniques described so that you can implement these approaches in your laboratory. Efficient audits are an outcome of using these approaches. Minimal time is spent creating checklists. In today’s hectic workplace this efficiency is needed. When an investigation requires an audit, you will learn how to narrow the focus of the audit and keep it on track. Economical audits are important. CO-CHAIR: DeAnn Benesh, 3M Food Safety CO-CHAIR: Patrice Arbault, Nexidia CO-CHAIR: Clotilde Teiling, Illumina • Presenters TBD 3:00 pm – 4:30 pm

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September 18–21, 2016

Sheraton Hotel, Dallas, Texas