AOAC-03 Preliminary Program

WILEY AWARD

WILEY AWARD ADDRESS ADVANCED STRATEGIES IN FOOD QUALITY, SAFETY, AND AUTHENTICITY CONTROL MONDAY, SEPTEMBER 19, 2016  |  1:00 PM – 1:30 PM Jana Hajšlová, Department of Food Analysis and Nutrition, Institute of Chemistry and Technology, Prague, Czech Republic In this year’s Wiley Award Address, at the 130th AOAC Annual Meeting and Exposition, in Dallas, Texas, USA, the recipient of the 2016 Harvey W. Wiley Award Jana Hajšlová , who is a research scientist at the Institute of Chemical Technology,

Prague, Czech Republic, will reflect on technical advances and challenges in food quality, safety, and authenticity control. On Monday, September 19, Hajšlová will present on the progress to date in food analysis, ongoing projects, and collaboration with AOAC. The field of food analysis has progressed significantly in recent decades, contributing to improved consumer health and reduced economic losses due to food fraud. Advances in instrumentation have driven improved method performance parameters. Data handling has also made considerable progress thanks to advanced software and databases. In addition, new strategies in food analysis have been developed, implemented, and tested in operational environments using, for example, ‘omics’ technologies, bioassay systems, mathematical modeling, quantitative structure-activity relationship models, and threshold of toxicological concern. For detecting contaminants and residues in food, notable innovations have changed the world of laboratory instrumentation. In the past, relatively low-resolution chromatography coupled with various element/group selective detectors was used. Today, validated methods based on high-resolution chromatographic separation followed by selective mass spectrometric (MS) detection are commonly used in trace analysis. Hundreds of analytes can make up the target list. Although this advanced instrumentation is widely available in modern laboratories, determination of possibly co- occurring groups of contaminants and residues is rarely carried out today in a single run. During the Wiley Award Address, Hajšlová will explain how advanced strategies are still needed for simultaneous determination of trace-level compounds. Such strategies are specifically needed for LC-MS-based methods used for trace analysis of emerging contaminants, including pesticide residues, mycotoxins, and natural toxins. To address this challenge, Hajšlová will examine how full-scanning, high-resolution mass spectrometry (HRMS) is becoming the preferred technology by laboratories for both qualitative and quantitative food analysis. This instrument can increase laboratory throughput, decrease sample handling workload, and, at the same time, address concerns on emerging contaminants. HRMS has begun to replace unit resolution main tandem mass spectrometry (using triple quadrupole mass analyzers) as the “gold standard.” HRMS offers major benefits such as nontarget screening (including a search of ´unknowns´) and retrospective data mining. Another technology more and more routinely used in food analysis for determination of sample composition, including minor components, is multi-dimensional separation, namely GCxGC coupled with time of flight detectors (TOF). It offers increased resolution for analysis of minor components and significantly reduces the number of false-positive/ false-negative results. Recently, added separation dimension has been applied, by inserting ion mobility (IM), to LC-MS systems. This technology also offers enormous potential and has opened the door to many challenging applications in food analysis. Isomers, conformers, and isobars can be resolved; cleaner mass spectra offer unbiased identification; and information can be obtained on molecules shape based on their differential behavior or velocity in an electric field.

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