2017_SBRT_Course Book

Prospective Study:

1194 pts;1-10 brain metastases 455 pts 1 metastasis

•

Median OS : 1 tumor 13,9 months (range 12.0-15.6) 2-4 tumors 10.8months(range 9.4-12.4) 5-10 tumors 10.8 months (Range 9.1-12.7)

531 pts 2-4 metastases 208 pts 5-10 metastases

Hypothesis :

•

No difference SRS 5-10 metastases to SRS 2-4 metastases

• Dose:

22Gy < 4ml 20 Gy 4-10ml