2017_SBRT_Course Book

Treatment related adverse events

Total (n=1194)

1 tumors N=455

2-4 tumors (B) N=531

5-10 tumors (C) N=208

P value B vs C

0.891

Treatment related advers events None Grade 1 and 2

1093 (92%) 69 (6%) 20 (2%) 8 (1%) 4 (<1%) 1132 (95%)

422 (93%) 22(5%) 6(1%) 3(1%) 2(<1%) 430 (95%)

481(91%) 36(7%) 10(2%) 3(1%) 1(<1%) 504 (95%)

190 (91%) 11(5%) 4(2%) 2(1%) 1(<1%) 198 (95%)

Grade 3 Grade 4 Grade 5 Had MMSE at baseline

• Grade 4 and 5 are very rare (less than 1%) in SRS of brain metastases. They may happen all groups of single-, oligo-, and multi-metastases