Quality Management 2017
Action limits - Proposed philosophy
Step 3:
Adjust the true dose probability distribution such that the dose limits IDC-C /2 and IDC+C /2 coincide with the clinical
tolerance
limits.
Prescribed dose
Probability distribution for the true dose
Dose (Gy)
TL
is set to a minimum acceptable cure rate
TL
is set to a maximum acceptable complication rate
Clinical tolerance limits
From Jörgen Olofsson (Dose Modeling and dose verification ESTRO COURSE)
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