IMRT

3D vs VMAT-TOMO: PTV

Cattaneo Radiot Oncol 2008

13 pts PTV 215- 745cc

Dose distribution: 3D vs TOMO 2.4 vs 1.4 (p<0.01) (TOMO benefit 42%)

PTV95%: 3D vs TOMO 92% vs 97.2% (p<0.01)

Rousseau Cancer Radioth 2012

10 pts PTV 723 (392-885 cc)

Conformity index: 3D 0.55±0.07 vs VMAT 0.89±0.07

(VMAT benefit 60%)