IMRT

3D vs IMRT: PTV Dose escalation in the target”

Schwartz IJROBP 2005

“Dose heterogeneity is an option to further escalate the dose in the target rather than a price to pay for using IMRT” Dose escalation 3D vs IMRT: 6% vs 17-35%

Grills IJROBP 2003

Dose escalation: IMRT>>25-30%

St Hilare Radiot Oncol 2009

Dose escalation: >78 Gy in 5/7 cases