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Biological Challenges that favor Particle Therapy
Radio-sensitivity
Squamous Cell Carcinoma (SCC)
(90%)
+++
Undifferentiated Carcinoma
++++
Adenocarcinoma
++
Adenoid-cystic carcinoma
*
,
Mucosal Melanoma
+
* Neutrons RBE:
adenoid-cystic carcinoma = 8.0
normal tissues (late effects) = 3 – 3.5